Tag: Omics

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Genomic approach to determine psychological and anatomic determinants of back pain

Back pain is the number one cause of years lived with disability worldwide and one of the most common reasons for health care visits in developed countries, yet surprisingly little is known regarding the biology underlying this symptom. In our previous study1, published in Sept 2018, we identified three novel genetic variants associated with chronic […]

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Different pleiotropic scenarios determine joint distribution of human metabolite levels

Adding covariates can either increase or decrease the power of finding an effect of a predictor on the outcome of interest. In a recent publication in GigaScience we used knowledge of biochemical networks to select covariates for conditional genetic association analysis. We demonstrated that the power depends on whether genes and environment play along or […]

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Chronic inflammation and low back pain

Last Thursday, July 5, 2018, a manuscript1 reporting results from a large multicentric case-control study of patients with chronic lower back pain (CLBP) was published in Biochimica et Biophysica Acta (BBA) – General Subjects. The work was funded by the EU FP7 project PainOmics in which we participate. The study of plasma N-glycome composition in patients […]

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Identification of sixty three multigenic modules involved in susceptibility to inflammatory bowel disease

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Crohn’s disease (CD) and ulcerative colitis (UC) are the principal types of inflammatory bowel disease.  IBD was virtually unheard of in the early nineteen hundreds. Since then it’s incidence (as well as that of a series of other inflammatory diseases including asthma) has dramatically […]

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https://www.mimomicsucam.com/

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Teaching at the Research MIMOmics Summer School in Cambridge (UK)

From 20 till 27 August, the EU FP7 consortium MIMOmics in which PolyOmica is a partner, organises a Summer School including a Workshop in Omics Studies. The goal of the School is to train a new generation of statistical omics scientists with a biological and biotechnological background to enable them to understand and to apply […]

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RSSSO2016 group photo

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The 2016 Research Summer School in Statistical Omics

We have just returned from Split, Croatia, where we organised and co-sponsored the third Research School in Statistical Omics (RSSSO2016). With this Summer School we aim to train young researchers (at bachelor, master or PhD level) with a bio{logical,medical,chemical} background and interest in quantitative statistical methods to become the next generation of life scientists; these […]

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